Publications – University of Copenhagen

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  1. K.R. Rosholm, N. Leijnse, A. Mantsiuo, V. Tkach, S.L. Pedersen, V.F. Wirth, L.B. Oddershede, K.J. Jensen, N.S. Hatzakis, P.M. Bendix, A. Callan-Jones, D. Stamou.
    Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells.
    Nature Chemical Biology, DOI:10.1038/nchembio.2372 (2017).

  2. L. Jauffred, R. Munk-Vejborg, K.S. Korolev, S. Brown, L.B. Oddershede.
    Chirality in microbial biofilms is mediated by close interactions between the cell surface and the substratum.
    ISME Journal, Nature Publ Group, DOI: 10.1038/ismej.2017.19 (2017).
  3. K. Norregaard, R. Metzler, C.M. Ritter, K. Berg-Sorensen, L.B. Oddershede.
    Manipulation and motion of organelles and single molecules in living cells.
    Chemical Reviews, accepted (2017).
  4. A. Bahadori, L.B. Oddershede, P.M. Bendix.
    Hot-nanoparticle-mediated fusion of selected cells.
    Nano Research, vol. 10, p. 2034-2045 (2017).

  5. A. Bahadori, L.B. Oddershede, P.M. Bendix.
    Optically controlled and selective fusion of cells and vesicles using plasmonic nano-heaters.
    Light Robotics - Structure-mediated Nanobiophotonics, Elsevier, ISBN: 9780702070969 (2017).
  6. C.M. Ritter, J. Mas, L. Oddershede, K. Berg-Sorensen.
    Quantifying force and viscoelasticity inside living cells using an active-passive calibrated optical trap.
    Optical Tweezers: Methods and Protocols, Methods in Molecular Biology, vol. 1486 p. 513-536, DOI 10.1007/978-1-4939-6421-5_20, Springer (2017).

  7. A.-K. V. West, L. Wullkopf, A. Christensen, N. Leijnse, J.M. Tarp, J. Mathiesen, J.T. Erler, L.B. Oddershede.
    Dynamics of cancerous tissue correlates with invasiveness.
    Scientific Reports, DOI: 10.1038/srep43800 (2017).

  8. J.M. Brickman, P. Serup.
    Properties of embryoid bodies.
    I: Developmental Biology, Vol. 6, Nr. 2, DOI: 10.1002/wdev.259 (2017).

  9. W.B. Hamilton, J.M. Brickman.
    Surveillance for secure differentiation.  
    I: Cell stem cell, Vol. 20, Nr. 1, 05.01.2017, s. 3-5, DOI: 10.1016/j.stem.2016.12.011 (2017).



  1. J. Tranekjaer Joergensen, K. Norregaard, P. Tian, P.M. Bendix, A. Kjaer, L.B. Oddershede.
    Single Particle and PET-based platform for identifying optimal plasmonic nano-heaters for photothermal cancer therapy.
    Scientific Reports, vol. 6 p. 30076-(1-10) (2016).
  3. Y.F. Barooji, A. Rorvig-Lund, S. Semsey, S.N.S. Reihani, P.M. Bendix.
    Dynamics of membrane nanotubes coated with I-BAR.
    Scientific Reports, vol. 6 p. 30054--(1-12) (2016).
  5. A. Bahadori, A.R. Lund, S. Semsey, L.B. Oddershede, P.M. Bendix.
    Controlled cellular fusion using optically trapped plasmonic nano-heaters.
    Proceedings of SPIE, vol. 9922 p. 1-10 (2016).
  7. C.M. Ritter, J.M. Brickman, L.B. Oddershede.
    Optical quantification of forces at play during stem cell differentiation.
    Proceedings of SPIE, vol. 9764 p. 97640J-(1-9) (2016).
  8. S.B. Dahl-Jensen, M. Figueiredo-Larsen, A. Grapin-Botton & K. Sneppen.
    Short-range growth inhibitory signals from the epithelium can drive non-stereotypic branching in the pancreas,
    Phys. Biol. 13 016007, DOI: 10.1088/1478-3975/13/1/016007 (2016).

  9. A. Bahadori, L.B. Oddershede, P.M. Bendix.
    Hot-nanoparticle-mediated fusion of selected cells.
    Nano Research.
    DOI: 10.1007/s12274-016-1392-3 (2016)

  10. M.J.Obersriebnig, E.M.H.Pallesen, K.Sneppen, A. Trusina, G. Thon.
    Nucleation and spreading of a heterochromatic domain in fission yeast.
    Nature Communications, Vol. 7, 11518 (2016).
    Doi: 10.1038/ncomms11518

  11. Raphaël B. Di Roberto, B. Chang, A. Trusina.
    Evolution of a G. protein-coupled receptor response by mutations in regulatory network interactions.
    Peisajovich, Sergio G. Nature Communications, Vol 7, 12344, 04.08.2016.
    Doi: 10.1038/ncomms12344. (2016)

  12. R.S. Illingworth, J.J. Hölzenspies, F.V. Roske, W.A. Bickmore, J.M. Brickman.
    Polycomb enables primitive endoderm lineage priming in embryonic stem cells.
    Elife, October 10, 5. pii: e14926. (2016)
    DOI: 10.7554/eLife.14926

  13. S. Vedel, H. Nunns, A. Košmrlj, S. Semsey, A. Trusina.
    Asymmetric Damage Segregation Consitutes an Emergent Population-Level Stress Response.
    Cell Systems. (13.07.2016).
    DOI: 10.1016/j.cels.2016.06.008

  14. M.L. Heltberg, R. Kellogg, S. Krishna, S. Tay, M.H. Jensen.
    Noise-induced NP-kB Mode Hopping Enables Temporal Gene Multiplexing.
    Cell Systems, 532-539, (21.12. 2016)
    DOI: 10.1016/j.cels.2016.11.014

  15. J.Martin Gonzalez, S.M. Morgani, R.A. Bone, K. Bonderup, S. Abelchian, C. Brakebusch, J.M. Brickman.
    Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency.
    Stem Cell Reports, 7 (2): 177:91. (09.08.2016)
    DOI: 10.1016/j.stemcr.2016.07.009

  16. C. Berclaz, A. Schmidt-Christensen, D. Szlag, J. Extermann, L.Hansen, A. Bouwens, M. Viliger, J. Goulley, F. Schuit, A. Grapin-Botton, T. Lasser, D. Holmberg.
    Longitudinal three-dimensional visualization of autoimmune diabetes by functional optical coherence imaging.
    Diabetologia, 59 (3): 550-9, (03.2016)
    DOI: 10.1007/s00125-015-3819-x

  17. J. Tranekjaer Joergensen, K. Norregaard, P. Tian, P.M. Bendix, A. Kjaer, L.B. Oddershede.
    Single Particle and Pet-based platform for identifying optimal plasmonic nano-heaters forphotothermal cancer thearapy.
    Scientific Reports, Vol. 6 p. 30076-(1-10). (2016).
    DOI: 10.1038/srep30076

  18. Anne Grapin-Botton
    Three-dimensional pancreas organogenesis models.
    Diabetes Obes Metab, Issue Supplement 1:33-40. Review. (18.09.2016)
    DOI: 10.1111/dom.12720

  19. C.Berclaz, D. Szlag, D. Nguyen, J. Extermann, A. Bouwens, P.J. Marchand, J. Nilsson, A. Schmidt-Christensen, D. Holmberg, A. Grapin.Botton, T. Lasser.
    Label-free fast 3D coherent imaging reveals pancreatic islet micro-vascularization and dynamic blood flow.
    Biomed Opt Express. 7 (11): 4569-4580. (17.10.2016)
    DOI: 10.1364/BOE.7.004569

  20. A. E. Moelgaard, I. Zettler, J.H. Dammeyer, S. Lehman, M.H.Jensen. J. Mathiesen.
    Measure of Node Similarity in Multilayer Networks.
    PloS One, e0146096, 14.06.2016.
    DOI: 10.1371/journal.pone.0157436

  21. P. Tian, K. Lindorff-Larsen, W. Boomsma, M. H. Jensen, J. Mathiesen.
    A Montecarlo study of the early steps of functional amyloid formation.
    PloS One, e0146096. (08.01.2016).
    DOI: 10.1371/journal.pone.0146096

  22. M. Rothová, J. J. Hölzenspies, A. Livigni, S.N. Villegas, J. M. Brickman.
    Differentiation of Mouse Embryonic Stem Cells into Ventral Foregut Precursors.
    Curr. Protoc. Stem. Cell Biol. , 3; 36: 1G. 3.1.-12. Review. PMID. (03.02.2016)
    DOI: 10.1002/9780470151808.sc01g03s36

  23. (Proceedings of SPIE)
    A. Bahadori, A.R.Lund, S. Semsey, L.B. Oddershede, P.M. Bendix.
    Controlled cellular fusion using optically trapped plasmonic nano-heaters.
    Proceedings of SPIE, Vol. 9922 p. 1-10 (2016).
    DOI: 10.1117/12.2237848
  24. (Proceedings of SPIE)
    C.M. Ritter, J. M. Brickman, L. B. Oddershede.
    Optical quantification of forces at play during stem cell differentiation.
    Proceedings of SPIE, vol. 9764 p. 97640J-(1-9). (2016)
    DOI: 10. 1117/12.2213377


  1. A. Grapin-Botton, P.A. Seymour & G. Gradwohl.
    Pairing-up SOX to kick-start beta cell genesis.
    Diabetologia, Vol. 58, No. 5, 05.2015, p. 859-861,
    DOI: (2015)
  2. A. Kosmrlj, P. Cordsen, A. Kyrsting, D.E. Otzen, L.B. Oddershede and M.H. Jensen.
    A monomer-trimer model supports intermittent glucagon fibril growth. 
    Scientific Reports 5, 9005 (2015) 
    DOI: 10.1038/srep09005
  3. A. Rørvig-Lund, A. Bahadori, S. Semsey, P.M. Bendix, L.B. Oddershede.
    Vesicle Fusion Triggered by Optically Heated Gold Nanoparticles.
    Nano Letters, vol. 15 p. 4183-4188 (2015). 
    DOI: 10.1021/acs.nanolett.5b01366
  4. A.F. Laing, S. Lowell & J. Brickman.
    Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression
    Developmental Biology, Vol. 397, No. 1, 01.01.2015, p. 56-66.
  5. C. Berclaz, C.  Pache, A. Bouwens, D. Szlag, A. Lopez, L. Joosten, S. Ekim, M. Brom, M. Gotthardt, A. Grapin-Botton & T. Lasser.
    Combined Optical Coherence and Fluorescence Microscopy to assess dynamics and specificity of pancreatic beta-cell tracers
    Scientific Reports, Vol. 5, 19.05.2015,
  6. C. Greggio, F. De Franceschi & A. Grapin-Botton.
    In Vitro-Produced Pancreas Organogenesis Models In Three Dimensions : Self-Organization From Few Stem Cells Or Progenitors.
    Stem Cells, Vol. 33, No. 1, 01.2015, p. 8-14.
  7. E.A. Ober & A. Grappin-Botton.
    At new heights - endodermal lineages in development and disease. Development (Cambridge, England), Vol. 142, No. 11, 01.06.2015, p. 1912-1917, DOI: 
  8. H. Klingberg, L.B. Oddershede, K. Loeschner, E.H. Larsen, S. Loft, P. Møller. Uptake of gold nanoparticles in primary human endothelial cells. Toxicology research, vol. 4 p.655-666 (2015) 
    DOI: 10.1039/c4tx00061g
  9. H. Klingberg, S. Loft, L.B. Oddershede, P. Møller.
    Influence of flow, shear stress and adhesion molecule targeting on gold nanoparticle uptake in human endothelial cells.
    Nanoscale, vol. 7 p. 11409-11419 (2015),
    DOI: 10.1039/C5NR01467K.
  10. J. Holzenspies, G. Dela Cruz & J. Brickman.
    Resolving Heterogeneity: Fluorescence-Activated Cell Sorting of Dynamic Cell Populations from Feeder-Free Mouse Embryonic Stem Cell Culture, Methods in molecular biology (Clifton, N.J.), 2015.
  11. K.M. Bendtsen, M.H. Jensen; S. Krishna & S. Semsey.
    The role of mRNA and protein stability in the function of coupled positive and negative feedback systems in eukaryotic cells, Scientific Reports, Vol. 5, 13910, 14.09.2015.
  12. L. Jauffred, S. Mohammad-Reza Taheri, R. Schmitt, H. Linke, L.B. Oddershede. Optical Trapping of Gold Nanoparticles in Air.
    Nano Letters, vol. 15 p. 4713-4719 (2015), 
    DOI: 10.1021/acs.nanolett.5b01366, also featured at  and on the Women in Nanoscience blog 
  13. L.A. Lemaire, J. Goulley,Y.H. Kim, S. Carat, P. Jacquemin, J. Rougemont, D.B. Constam & A. Grapin-Botton.
    Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis.
    Development (Cambridge, England), Vol. 142, No. 5, 01.03.2015, p. 858-70.
  14. L.B. Oddershede.
    Voices of chemical biology.
    Nature Chemical Biology, vol. 11 p.378-379, 446-447, 752-753 (2015).
    DOI: 10.1038/nchembio.1820
  15. N. Leijnse, L.B. Oddershede, P.M. Bendix.
    An updated look at actin within filopodia. Cytoskeleton, vol.72 p.71-79 (2015).
  16. N. Leijnse, L.B. Oddershede, P.M. Bendix.
    Dynamic buckling of actin within filopodia.
    Communicative and Integrative Biology, vol.8 p. e1022010-(1-3) (2015).
    DOI: 10.1080/19420889.2015.1022010,
  17. N. Leijnse, L.B. Oddershede, P.M. Bendix.
    Helical buckling of actin inside filopodia generates traction. PNAS, vol. 112 p. 136-141 (2015),,
  18. N. Mitarai, M.H. Jensen, S. Semsey.
    Coupled positive and negative feedbacks produce diverse gene expression patterns in colonies, mBio, Vol. 6, Nr. 2, e00059, 07.04.2015.
  19. P. Tian, W. Boomsma, Y. Wang, D.E. Otzen, M.H. Jensen and K. Lindorf-Larsen. Structure of a Functional Amyloid Protein Computed Using Sequence Variation, J. Am. Chem. Soc., 137, pp 22 - 25.
    DOI: 10.1021/ja5093634 (2015)
  20. R.K. Schmitt, L. Jauffred, S. Mohammad-Reza Taheri, H. Linke, L.B. Oddershede. Optical trapping of gold aerosols. Proceedings of SPIE, vol. 9548 p.95480F-1 (2015)
  21. T.C.T Michaels, P. Yde, J.C.W Willis, D. Otzen, C.M. Dobson, A.K. Buell, T.P.J. Knowles, The length distribution of frangible biofilaments, Journal of Chemical Physics, Vol. 143, Nr. 16, 28.10.2015,
  22. Y.A. Kim, H. Larsen, P. Rué, L.A. Lemaire, J. Ferrer & A. Grapin-Botton.
    Cell cycle-dependent differentiation dynamics balances growth and endocrine differentiation in the pancreas.
    P L o S Biology, Vol. 13, No. 3, 03.2015, p. e1002111.
  23. S.M. Morgani & J.M. Brickman (2015).
    LIF supports primitive endoderm expansion during pre-implantation development.
    Development 2015 142: 3488-3499.
    DOI: 10.1242/dev.125021
  24. K. Koltowska, AK Lagendijk, C Pichol-Thievend, JC Fischer, M Francois, EA Ober, A.S. Yap, BM. Hogan. (2015)
    Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish”.  
    DOI: 10.1016/j.celrep.2015.10.055